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PPARδ Agonist

GW-0742

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Overview

A selective PPARδ agonist used as a laboratory tool compound; no human data, and it shares the PPARδ-class carcinogenicity concern.

How it works

GW-0742 is a close chemical relative of cardarine — another selective PPARδ agonist — used mainly as a laboratory tool to study that receptor.

It works the same way: switching on PPARδ to drive the genes for fat metabolism and mitochondrial activity.

Because it shares the PPARδ mechanism, it also shares the class-level cancer concern that ended cardarine's development. There is no human data, and it's a research chemical rather than a therapeutic.

Mechanism · Detailed Analysis
Molecular targetA selective PPARδ agonist used as a laboratory tool compound.
Signaling & downstream effectsThe same PPARδ/RXR transcriptional program as cardarine.
CaveatsCarries the PPARδ-class carcinogenicity concern; no human data.
Published EvidenceLoading cited studies from PubMed…
Human Data ···

Searching the published record…

Animal ···

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In Vitro ···

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Educational aggregation of public literature. Not medical advice and not a recommendation to use any compound. Many compounds here are not approved for human use. Consult a licensed clinician.