Sign in
← Database
Nootropic

Noopept

Shop · Omnichems ↗Buy · Disguised Alpha ↗
Third-party suppliers · research use only · not an endorsement. Some links are affiliate links — purchases made through them may earn this site a commission.
Overview

A proline-containing dipeptide marketed as a cognitive enhancer; clinical evidence is mostly Russian and limited in scale/quality.

How it works

Noopept is a synthetic dipeptide developed in Russia, related in spirit to the racetam nootropics and marketed as a cognitive enhancer.

It's partly converted in the body to a compound (cycloprolylglycine) thought to be active, and its proposed mechanisms include modulating the brain's glutamate (AMPA/NMDA) signaling and raising growth factors like BDNF and NGF.

As with several Russian-developed nootropics, the clinical evidence is mostly Russian and limited in scale and quality, so the mechanism is better described as plausible than proven.

Mechanism · Detailed Analysis
Molecular targetA proline-containing dipeptide, metabolised in part to cycloprolylglycine.
Proposed downstream effectsProposed modulation of AMPA/NMDA glutamate signalling and upregulation of BDNF/NGF.
Evidence & caveatsCognitive-enhancement evidence is mostly Russian and limited in scale and quality.
Published EvidenceLoading cited studies from PubMed…
Human Data ···

Searching the published record…

Animal ···

Searching the published record…

In Vitro ···

Searching the published record…

Educational aggregation of public literature. Not medical advice and not a recommendation to use any compound. Many compounds here are not approved for human use. Consult a licensed clinician.